There are currently three long-acting injectible antipsychotic medications on the market. They are: haloperidol (Haldol Decanoate), perphenazine (Prolixin Decanoate) and risperidone (Risperdal Consta). For people with bipolar disorder, these medications would likely only be used if prone to frequent recurrence of psychosis.
These three long-acting versions can be helpful when working with people who frequently discontinue medications or who would prefer to have fewer pills to take on a daily basis. Studies comparing long-acting medications to the pill form show that people have fewer relapses with psychotic symptoms when on the long-acting version. Prior to starting a long-acting injectible, it’s standard practice to use the pill form first to ensure that the person is able to tolerate the medication and doesn’t have any adverse reactions. Depending on the medication chosen, the frequency of dosing will be every two to four weeks.