These vaccines should not be given to anyone who has had a severe allergic reaction to a previous dose of the vaccine or to any component in the vaccine. In addition, people who are moderately or severely ill should be cautioned against receiving this vaccine until they recover from their illness.
Children who had encephalopathy or a coma within seven days of a previous DTaP vaccine should never receive another DTaP or Tdap vaccine. In addition, children who have a progressive or unstable neurological condition, such as uncontrolled seizures, or progressive encephalopathy, should not receive the vaccine until their neurological status has stabilized. Children who have a stable neurological condition, such as cerebral palsy, should receive the vaccine.
Children who had a moderate or severe reaction to a previous dose of DTaP should discuss the option of using the DT vaccine without a pertussis component for subsequent vaccines in the series. Such reactions might include shock or collapse, a seizure, a fever greater than or equal to 105ºF, or nonstop crying for more than three hours after a previous dose of DTaP.
People considering the Tdap vaccine should talk to their doctor if they have ever had Guillain-Barré syndrome (GBS) in the past.
The DTaP and DT vaccines are only approved for children under the age of seven years. The Td and tetanus alone vaccines are only recommended for people seven years of age and older. The two types of Tdap vaccine are approved for different ages, but together they cover a range of people aged ten to sixty-five years.