When an unsolved mystery is afoot, clues are always welcome. But clues are just that, clues. They can produce a viable hunch and help lead you in the direction of finding the answers to solving the mystery, but they are not the answers themselves.
Genetic test results for celiac disease can either be an answer or a clue. Genetic testing is a rule out test for celiac disease: It does not conclusively determine that you have it; if the test is negative, it rules out the possibility that you have or could develop the disease (an answer). But a positive result means only that you may have celiac disease or could develop it. The test is only an indicator for the possibility of the disease by revealing the presence of the gene, but it is not a diagnosis (only a clue). The ultimate answer is a positive diagnosis through an intestinal biopsy. Keep in mind that you could have the genetic marker and still have a negative intestinal biopsy. This could mean that you may have not developed the disease yet, you may never develop it, or it is latent.
According to Prometheus Therapeutics & Diagnostics in San Diego, California, approximately 37 percent of the United States population has the genetic marker for celiac disease. But not all people who carry the marker will develop the disease. And keep in mind that a negative result does not mean that you are not gluten intolerant or gluten-sensitive.